Girguis was raised in Cairo, Egypt, as well as Abu Dhabi, UAE. Upon finishing high school, he moved to the United States to pursue his college education. He earned his Bachelor's Degree in Mechanical Engineering from Louisiana State University in 2017. Afterward, he moved to the University of Maryland, College Park, where he pursued a Ph.D. in Aerospace Engineering with a focus on unsteady aerodynamics.

As a Ph.D. candidate, he experimentally studied the fundamental flow physics during large-amplitude wing-gust encounters and the developed effective closed- and open-loop control strategies for gust alleviation. In the summer of 2019, he served as a visiting scholar at the University of Cambridge under the International Student Exchange Program, guided by Professor Holger Babinsky, where he developed a cost-effective computational discrete-vortex platform to accurately model unsteady wing-gust encounters and prototype gust-mitigating closed-loop control strategies.

Girguis was also a member of the UMD Future Faculty Program. As a future faculty fellow, he instructed a graduate course on unsteady aerodynamics and an undergraduate course on incompressible aerodynamics. Upon completing his Ph.D., he transitioned to Princeton University for his postdoctoral research at the BAM lab, focusing on bio-inspired aerodynamics and design.